Rare Diseases and Orphan Drugs shows that much of what we now know about common diseases has been achieved by studying rare diseases. It proposes that future advances in the prevention, diagnosis, and treatment of common diseases will come as a consequence of our accelerating progress in the field of rare diseases. Understanding the complex steps in the development of common diseases, such as cancer, cardiovascular disease, and metabolic diseases, has proven a difficult problem.

Rare diseases...

The Craft and Science of Coffee follows the coffee plant from its origins in East Africa to its current role as a global product that influences millions of lives though sustainable development, economics, and consumer desire. For most, coffee is a beloved beverage. However, for some it is also an object of scientifically study, and for others it is approached as a craft, both building on skills and experience.

By combining the research and insights of the scientific community and expertise o...

Encyclopedia of Cancer, Third Edition, provides a comprehensive, up-to-date overview of the multiple facets of the disease, including research, treatment and societal impact. This new edition comprises 180 contributions from renown experts who present the latest in Mechanisms, Hallmarks of Cancer, Causes of Cancer, Prevention and Control, Diagnosis and Therapy, Pathology and the Genetics of specific Cancers. Readers will find a comprehensive overview of the main areas of oncology, including e...

Comprehensive Biotechnology, Third Edition, Six Volume Set unifies, in a single source, a huge amount of information in this growing field. The book covers scientific fundamentals, along with engineering considerations and applications in industry, agriculture, medicine, the environment and socio-economics, including the related government regulatory overviews. This new edition builds on the solid basis provided by previous editions, incorporating all recent advances in the field since the se...

Now in its fourth edition, Vascular Ultrasound offers a compact yet comprehensive practical guide for anyone working in the field of vascular sonography.

The book is written by expert practitioners as an easily accessible reference, providing key information suited to sonographers in their day-to-day practice. It covers essential vascular investigations undertaken by ultrasound departments and vascular laboratories in more detail than general ultrasound textbooks, but without overwhelming son...

MORE THAN AN ATLAS Studying anatomy is fun! Recognising the structures on the dissection, understanding their relationships and gaining an overview of how they work together assures confident study and transition into clinical practice. The Sobotta Atlas shows authentic illustrations of the highest quality, drawn from genuine specimens, guaranteeing the best preparation for the gross anatomy class and attestation. Sobotta focuses on the basics, making it totally comprehensive.

Every tiny stru...

Current, comprehensive, and evidence-based Braunwald's Heart Disease remains the most trusted reference in the field and the leading source of reliable cardiology information for practitioners and trainees worldwide. The fully updated 12th Edition continues the tradition of excellence with dependable, state-of-the-art coverage of new drugs, new guidelines, more powerful imaging modalities, and recent developments in precision medicine that continue to change and advance the practice of cardio...

Doing Bayesian Data Analysis: A Tutorial with R, JAGS, and Stan, Second Edition provides an accessible approach for conducting Bayesian data analysis, as material is explained clearly with concrete examples. Included are step-by-step instructions on how to carry out Bayesian data analyses in the popular and free software R and WinBugs, as well as new programs in JAGS and Stan. The new programs are designed to be much easier to use than the scripts in the first edition.

In particular, there ar...

International Encyclopedia of Human Geography, Second Edition, Fourteen Volume Set embraces diversity by design and captures the ways in which humans share places and view differences based on gender, race, nationality, location and other factors—in other words, the things that make people and places different. Questions of, for example, politics, economics, race relations and migration are introduced and discussed through a geographical lens. This updated edition will assist readers in the...

A mononeuropathy has to be recognised through physical examination before it can be explained and treated. This practical book provides valuable guidance on examination of peripheral nerves, and then looks at possible causes, prognosis and treatment. Mononeuropathies of the arm, leg and trunk are covered, and causes of mononeuropathies other than focal lesions are included.

The easy to follow text is well illustrated with over 90 line diagrams.practical book in the style of Aids to the Examin...