A thorough understanding of cellular and molecular mechanisms involved in the individual expression of toxic effects provides an important tool for assessment of human health risk. New aspects, major advances, and new areas in molecular and cellular biology and toxicology demand updated sources of information to elucidate the functional mechanics of human toxicology. Mechanistic Toxicology: The Molecular Basis of How Chemicals Disrupt Biological Targets, Second Edition retains the accessible ...

-Number one text for depth and comprehensive coverage: detailed analysis of existing knowledge and practice -Comprehensively updated in 7th edition with latest research findings, theoretical developments and applications to practice. -Well structured and easily navigable: topic areas clearly defined and packaged to fit course delivery -Unmatched authority: highly recognized author and five previously successful editions -Links theory to practice to help students learn and apply key skills -Of...

Despite the recent rapid growth in machine learning and predictive analytics, many of the statistical questions that are faced by researchers and practitioners still involve explaining why something is happening. Regression analysis is the best ‘swiss army knife’ we have for answering these kinds of questions.

This book is a learning resource on inferential statistics and regression analysis. It teaches how to do a wide range of statistical analyses in both R and in Python, ranging from s...

This book explains the ways of transforming business models from supply driven to demand driven through digital technologies and big data analytics. It covers important topics such as digital leadership, the role of Artificial Intelligence, and platform firms and their role in business model transformation.

Public Management and Governance is the leading text in international public management and governance and an ideal introduction to all aspects of this field. It combines rigorous insight from pre-eminent scholars around the world with supportive, thoughtful, and intuitive structure and pedagogy. This revised and updated fourth edition responds to the significant changes in the external environment, as well as the field itself.

It includes six new chapters covering aspects of increasing impor...

Modern Mandarin Chinese Grammar: A Practical Guide, third edition, is an innovative reference guide to Mandarin Chinese, combining traditional and function-based grammar in a single volume. The Grammar is divided into two parts. Part A covers traditional grammar points such as phrase order, and the structure of noun phrases and verb phrases.

Part B is carefully organized around language functions and situations such as:Asking questionsCommunication strategiesMaking comparisonsGiving orders an...

What does the collapse of sub-prime lending have in common with a broken jackscrew in an airliners tailplane? Or the oil spill disaster in the Gulf of Mexico with the burn-up of Space Shuttle Columbia? These were systems that drifted into failure. While pursuing success in a dynamic, complex environment with limited resources and multiple goal conflicts, a succession of small, everyday decisions eventually produced breakdowns on a massive scale. We have trouble grasping the complexity and nor...

Psychology for Nurses and Health Professionals, Second Edition is an accessible guide providing comprehensive coverage of psychology for nurses and healthcare professionals in training and practice. Key features include: Fully updated and restructured to ensure content matches training requirements for nurses and healthcare practitioners Stronger focus on the biopsychosocial model, therapeutic relationships and self-awareness More examples to highlight application with theories demonstrated t...

Since the turn of the twenty-first century, the psychology of emotion has grown to become its own field of study. Because the study of emotion draws inspiration from areas of science outside of psychology, including neuroscience, psychiatry, biology, genetics, computer science, zoology, and behavioral economics, the field is now often called emotion science or affective science. A subfield of affective science is affective neuroscience, the study of the emotional brain.

This revised second ed...

Skills for Communicating with Patients, Third Edition is one of two companion books on improving communication in medicine, which together provide a comprehensive approach to teaching and learning communication skills throughout all levels of medical education in both specialist and family medicine. Since their publication, the first edition of this book and its companion, Teaching and Learning Communication Skills in Medicine, have become established standard texts in communication skills te...